enzyme nomenclature and classification pdf

Enzyme nomenclature and classification pdf

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Table of Contents

Enzyme Definition and Classification

Description

Table of Contents

Since many enzymes have common names that do not refer to their function or what kind of reaction they catalyze, an enzyme classification system was established. There were six classes of enzymes that were created so that enzymes could easily be named. Enzymes are normally used for catalyzing the transfer of functional groups, electrons, or atoms. Since this is the case, they are assigned names by the type of reaction they catalyze. The enzymes were numbered and from here, they were divided into subdivisions.

A simple web-based query interface is provided, along with an advanced search engine for more complex Boolean queries. An associated form-based curatorial application has been developed to facilitate the curation of enzyme data as well as the internal and public review processes that occur before an enzyme entry is made official. The assignment of EC numbers and preparation of descriptive entries for each enzyme is coordinated by our group at Trinity College Dublin. Enzymes are classified according to the reactions they catalyse. Each enzyme, or group of enzymes that catalyse the same reaction, is given a four-part EC number, each part of which provides information about the reaction s catalysed. The structure of the catalytic molecule is not taken into account in the classification process so enzymes with different structures that catalyse the same reaction will have the same EC number.

Enzyme Definition and Classification

Enzyme , a substance that acts as a catalyst in living organisms, regulating the rate at which chemical reactions proceed without itself being altered in the process. A brief treatment of enzymes follows. For full treatment, see protein: Enzymes. The biological processes that occur within all living organisms are chemical reactions , and most are regulated by enzymes. Without enzymes, many of these reactions would not take place at a perceptible rate. Enzymes catalyze all aspects of cell metabolism.

Description

The Enzyme Commission number EC number is a numerical classification scheme for enzymes , based on the chemical reactions they catalyze. Strictly speaking, EC numbers do not specify enzymes, but enzyme-catalyzed reactions. If different enzymes for instance from different organisms catalyze the same reaction, then they receive the same EC number.

Enzyme Nomenclature is based upon the recommendations of the Nomenclature Committee of the International Union of Biochemistry on the Nomenclature and Classification of Enzymes. This book deals with the naming of enzymes. The text describes problems encountered in the past when individual scientists named enzymes randomly, resulting in duplication, misnomers, and confusion.

Metrics details. The data, which are stored in a MySQL database, preserve the formatting of chemical and enzyme names. A simple, easy to use, web-based query interface is provided, along with an advanced search engine for more complex queries.

Introduction to Enzymes

An enzyme is a protein or RNA produced by living cells, which is highly specific and highly catalytic to its substrates. Enzymes are a very important type of macromolecular biological catalysts.

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